Little Things Factory GmbH

Ueber der Bitz 3
Elsoff,  D-56479

  • Booth: A407

microreactors, lab-on-a-chip, flow chemistry

As a leading supplier in the fields of fluidics and microreaction technology, the Little Things Factory develops and produces high-quality components and systems solutions in glass, quartz and glass-silicon composite materials for a variety of sectors. Typical applications in the fields of life science, chemistry and research and development are lab-on-chip products as well as microreactors of the kind required in the fields of diagnostics, medicine distribution and implantology or the manufacture of special chemicals. The Little Things Factory has many years of expert knowledge in the design and application of optical, electronic and chemical functions within a wafer as the basis for microstructured processes. The company has thus become a sought-after partner for technology concerns, research institutions and universities alike.

 Press Releases

  • Elsoff. Little Things Factory GmbH (LTF) and Sigma-Aldrich® Corporation have signed a global distribution agreement for a number of glass microreactors produced by Little Things Factory. The products can now be purchased worldwide through the Sigma-Aldrich catalogue and are available online at

    "Our distribution agreement with Sigma-Aldrich ensures scientists around the globe will have easy access to our high-performance microreactors," said Alexander Schilling, CEO of Little Things Factory GmbH. "Scientists will benefit through the exceptional service provided by Sigma-Aldrich's global supply chain and distribution network."
    "Our collaboration with Little Things Factory offers the global scientific community an enhanced line of high-quality microreactors to support the growing interest in this area of life science," added Pietro Butti, Product Manager at Sigma-Aldrich.

    About Sigma-Aldrich:

    Sigma-Aldrich is a leading Life Science and High Technology company whose biochemical, organic chemical products, kits and services are used in scientific research, including genomic and proteomic research, biotechnology, pharmaceutical development, the diagnosis of disease and as key components in pharmaceutical, diagnostics and high technology manufacturing. Sigma-Aldrich customers include more than one million scientists and technologists in life science companies, university and government institutions, hospitals and industry. The Company operates in 40 countries and has nearly 9,000 employees whose objective is to provide excellent service worldwide. Sigma-Aldrich is committed to accelerating customer success through innovation and leadership in Life Science, High Technology and Service. For more information about Sigma-Aldrich, please visit its website, at

    Sigma-Aldrich and Sigma are trademarks of Sigma-Aldrich Co. LLC registered in the US and other countries
  • Elsoff. The Little Things Factory is now in the position to offer a wide range of reactors and fluidic chips made of quartz (fused silica). In contrast to other glass materials, quartz glass provides a variety of advantageous product properties. These include inter alia high transmission in the ultraviolet range, low thermal expansion, very high temperature stability, very high thermal resistance, very high thermal shock resistance, high purity of the material, low own fluorescence. 

    Therefore, customers could use the highest mixing efficiency with maximum UV-transmission and thus discover new standards in the photochemistry industry. All components will be fused by innovative bonding processes, to ensure maximum stability and chemical resistance.
  • The Nelson Mandela University launches a project to manufacture medicines against AIDS, tuberculosis and malaria

    Elsoff. Little Things Factory GmbH (LTF) produces high quality components such as microreactors required in the fields of life sciences, medical distribution or the production of special chemicals. The outstanding technology from LTF is therefore perfectly suited for the development of vital medicines.

    The Nelson Mandela University launches project for the production of AIDS drugs and other advanced pharmaceutical substances

    The Nelson Mandela University in South Africa is currently implementing a project to manufacture vital drugs. The destination of the research team is to improve pharmaceutical production, so South Africa can produce its own substances for the medicines. These drugs will then be used primarily for diseases such as AIDS, tuberculosis and malaria. Currently, original medicines are only being developed in Europe and the USA. China and India, however, produce much cheaper generics.These generics are imported from South Africa, whereby in spite of the cheaper prices billions of rand were spent. Making their own medicines ensures that people in South Africa have access to the latest pharmaceutical developments. In addition, local production can save the country a lot of money.

    Flow reactors of LTF are used for drug research

    For the development of drug manufacturing the team from the Nelson Mandela University uses flow reactors, which are manufactured by LTF in Germany. These reactors are part of the latest equipment from the National Research Foundation, which makes it possible to carry out the project at all. "Making their own medicines in South Africa is an important step forward and an asset to the locals. We are very proud to be part of this progress!" Alexander Schilling, Managing Director of LTF, reports.

    For the first time a project of the Nelson Mandela University will be presented at a major convention

    The Nelson Mandela University project is now being presented for the first time at BIO Africa Convention taking place from August 27-29 at ICC Durban in South Africa. For the successful further implementation of the project, an application has already been submitted for an unrestricted commercial facility for the manufacture of AIDS medicines.

    About LTF GmbH:
    As a leading supplier in the fields of fluidics and microreaction technology, Little Things Factory develops and produces high-quality components and system solutions made of glass, quartz and glass-silicon composite materials for a variety of sectors. The product range includes fluidic chips as well as microreactors for lab-on-chip, life science, flow chemistry, photochemistry and R&D applications.

    About Nelson Mandela University:
    Nelson Mandela University is a state university in South Africa. About 27,000 students study in the fields of humanities, health sciences, engineering, information technology, economics, education, law and science. Further information at


    Microreactors can be built by the Little Things Factory in sizes up to 300mm x 300mm......

  • Microreactors can be built by the Little Things Factory in sizes up to 300mm x 300mm. The height is dependent on the number of function levels and their thickness. The various functions are achieved modularly through design elements within a layer, as well as spanning the various layers.


    The Little Things Factory GmbH develops and manufactures standard reactors for microreaction technology from glass. This material is ideally suited for these applications, since it is also resistant to difficult environmental influences, such as, for example, high temperatures and chemicals, and at the same time displays a high degree of biocompatibility.


    The fluid components of the Little Things Factory can be directly screwed onto each other or linked by means of connecting elements such as pipes or hoses. Sensors and valves are integrated into double muff couplings which have been specially designed to accommodate them.


    Microreactors with a microstructured inner structure are assembled by the Little Things Factory with a free choice of design; they are application-specific in accordance with customer requirements and use glass, quartz, silicon and glass/silicon combinations.
    Little Things Factory supplies lab on chip components made of glass, quartz and glass-silicon composite materials......

  • Little Things Factory supplies lab on chip components made of glass, quartz and glass-silicon composite materials. These components are used as micro reactors in the field of medical and pharmaceutical technology as well as in the form of fluidic chips in the field of diagnostics, medical applications and implantology.

    As materials glass, quartz and glass-silicon combinations are ideal for these applications, since they are materials which can resist difficult environmental conditions such as, for example, high temperatures and chemicals. They nonetheless demonstrate a high degree of bio-compatibility. These characteristics distinguish the materials markedly from the polymer substances standardly used in these fields of application.

    For the creation of fluidic components and bio-chips Little Things Factory uses a wide range of structuring processes which have been employed for many years in the field of MEMS cap wafers, including, for example, micro-sandblasting and wet-chemical structuring of glass and quartz.The manufacture of these fluidic chips can be carried out inexpensively based on 6" or 8" wafers.

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